Head of Clinical Research Science
Employment Information
Report this job
Job expired or something wrong with this job?
Job Description
Head of Clinical Research Science leading Ciliatech’s European ophthalmic clinical studies and evidence strategy. Guiding medical device development, regulatory documentation and clinical research teams.
Responsibilities:
- Lead Ciliatech’s European clinical and research activities
- Strengthen the scientific understanding of Ciliatech’s technology and products
- Develop and integrate scientific, preclinical and clinical evidence for clinical development, product performance, new indications and product development decisions
- Provide strategic and scientific oversight of Ciliatech-sponsored European clinical studies
- Work cross-functionally across Research & Development, Clinical, Medical, Quality and Regulatory functions
- Conduct and synthesise literature reviews, data mining and quantitative analyses
- Identify scientific and clinical knowledge gaps, unexplained outcomes and factors influencing product performance and clinical outcomes
- Formulate scientific hypotheses and propose evidence-generation plans
- Design and coordinate occasional preclinical research activities
- Translate scientific, preclinical and clinical findings into recommendations for leadership and functional teams
- Define or review study concepts, scientific rationale, objectives, endpoints and protocol assumptions
- Review study progress, emerging data, risks and scientific or operational issues
- Analyse and interpret clinical study results with scientific, medical, statistical and regulatory experts
- Maintain integrated scientific, preclinical and clinical evidence supporting products
- Investigate patient selection, surgical technique, device positioning, product performance and clinical outcomes
- Prepare or contribute to scientific abstracts, manuscripts, congress presentations, internal reports and peer-reviewed publications
- Maintain and update clinical sections of technical documentation supporting CE marking
- Prepare or contribute to Clinical Evaluation, PMCF and other applicable MDR clinical documentation
- Provide scientific and clinical input for responses to Notified Bodies and regulatory stakeholders
- Lead the European clinical and research function; define roles, priorities and resource needs
- Provide line management and strategic direction to the Senior Project Manager and assigned clinical personnel or contractors
- Coordinate interfaces across Research & Development, Clinical, Medical, Quality and Regulatory functions
Requirements:
- Advanced degree in life sciences, biomedical sciences, medicine, pharmacy, engineering or another relevant scientific discipline
- Significant senior experience in scientific research, clinical research and/or medical device development
- Strong experience in ophthalmology
- Experience developing scientific hypotheses and interpreting scientific, preclinical and clinical data
- Experience designing or overseeing clinical and/or preclinical studies
- Experience working cross-functionally with R&D, Clinical, Medical, Quality and Regulatory functions
- Experience leading clinical or scientific professionals and coordinating external partners
- Strong scientific reasoning, literature-review and hypothesis-driven research skills
- Ability to analyse and interpret scientific, preclinical and clinical data, including basic biostatistical outputs
- Strong understanding of clinical research methodology and study design
- Strong scientific and technical writing and presentation skills
- Knowledge of Good Clinical Practice, ISO 14155 and applicable European clinical research requirements
- Knowledge of EU MDR, Clinical Evaluation and PMCF
- Strategic leadership, prioritisation, delegation and people-management skills
- Ability to lead through influence across employees, contractors and external experts
- Professional fluency in English
- Ability to travel independently as required for clinical studies, scientific collaborations and meetings with external partners
- Regular European travel readiness
- Preferred: PhD, PharmD, MD or equivalent advanced scientific degree, preferably in ophthalmology, glaucoma, medical devices or biomedical research
- Preferred: Experience in glaucoma or implantable ophthalmic medical devices
- Preferred: Experience with European medical device clinical development and MDR clinical documentation
- Preferred: Experience managing CROs, laboratories, investigators and academic partners
- Preferred: Previous line-management responsibility in a clinical, scientific or R&D function
- Preferred: Hands-on experience with data mining, numerical simulation or translational research
- Preferred: Scientific expertise in glaucoma pathophysiology, aqueous humour outflow or glaucoma surgery
Benefits:
- Fully remote work arrangement
- Ability to work regularly from the office for candidates based in France
- Regular European travel and occasional international travel as required
- Scientific and professional development through clinical studies, collaborations, meetings, laboratories, scientific meetings and congresses
Similar Jobs
Senior Clinical Research Associate
Senior Clinical Research Associate overseeing site monitoring and compliance for ICON’s sponsor-dedicated clinical trials. Supporting data integrity, site performance, and successful trial execution.
Business Development Director, Clinical Research
Business Development Director driving CRO sales and strategic accounts for Ergomed’s clinical research services. Building pharmaceutical and biotechnology client relationships across the UK and Nordic markets.
Business Development Director, Clinical Research
Business Development Director growing Ergomed’s clinical research services across the UK and Nordics. Securing pharmaceutical and biotechnology contracts through strategic sales and client partnerships.
Clinical Research Associate II
Clinical Research Associate II monitoring clinical trials for ICON’s sponsor-dedicated research programs. Ensuring protocol compliance, data integrity, and patient safety across study sites.
Principal Biostatistician
Principal Biostatistician supporting clinical-trial development at Precision Medicine Group, a life-sciences consultancy. Leading statistical analyses, SAS programming, study oversight, and sponsor collaboration.
Principal Biostatistician
Principal Biostatistician supporting statistical design, analysis, and reporting for Precision for Medicine’s clinical trials. Leading SAS programming, sponsor collaboration, and global biostatistical oversight.
Senior Clinical Research Associate
Senior Clinical Research Associate monitoring clinical trial sites for ICON in Milan, Italy. Ensuring protocol compliance, data integrity, and successful sponsor-dedicated trial execution.
Clinical Research Associate – 3
Clinical Research Associate overseeing Australian clinical trial sites for ICON's sponsor-dedicated research programs. Monitoring protocol compliance, site performance, data integrity, and CRA training.
Senior Manager, Clinical Data Management
Clinical data management leader overseeing Kite’s non-interventional and investigator-sponsored studies. Supporting cancer immunotherapy development through CDM strategy, compliance, vendors, and cross-functional delivery.
Clinical Research Associate – Home-based
Freelance CRA overseeing approximately 10 Czech study sites for Alcedis, a German clinical research organization. Managing monitoring, regulatory submissions, contracts, and international study coordination.
Senior Clinical Research Associate
Senior Clinical Research Associate monitoring oncology and onco-hematology clinical trials for BeOne. Managing German sites, regulatory compliance, study milestones, and junior CRA mentorship.
Trial Delivery Specialist – Clinical Trial Coordinator
Clinical Trial Coordinator supporting Thermo Fisher Scientific’s global clinical studies. Managing trial operations, vendors, eTMF oversight, supplies, budgets, and cross-functional delivery.
Senior Clinical Research Associate – CNS
Senior Clinical Research Associate monitoring CNS clinical trials across Czechia for Worldwide Clinical Trials, a global contract research organization. Managing sites, compliance, data quality, and study closeout.
Freelance Clinical Research Associate
Freelance Clinical Research Associate monitoring clinical trials for TFS HealthScience, a global contract research organization. Ensuring site compliance, participant safety, data integrity, and regulatory quality.
Clinical Research Associate
Clinical Research Associate monitoring ophthalmology clinical trials for global CRO TFS HealthScience. Ensuring site compliance, participant safety, data integrity, and accurate study documentation.
Senior Clinical Data Manager – Contract
Sr. Clinical Data Manager overseeing global clinical trial data management for BioCryst. Coordinating CROs, vendors, data cleaning, database locks, and regulatory submission support.
Senior Clinical Research Associate, 0.5 FTE
Senior Clinical Research Associate supporting Parexel’s oncology clinical trials in Belgium. Ensuring site compliance, patient safety, data integrity, and inspection readiness through remote and on-site monitoring.
Senior Clinical Trial Manager
Senior Clinical Trial Manager executing clinical studies for AbbVie, a company developing innovative medicines and health solutions. Supporting cross-functional teams, vendors, training, and study documentation.
Clinical Trial Manager
Clinical Trial Manager overseeing sponsor-dedicated clinical studies for ICON in São Paulo, Brazil. Managing trial delivery, compliance, stakeholders, vendors, and clinical programme quality.
Principal Biostatistician
Principal Biostatistician supporting Thermo Fisher Scientific’s clinical research programs. Applying SAS, CDISC, and statistical methodology from study design through final reporting.