Associate Director – Health Economics & Outcomes Research, Oncology
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Job Description
HEOR leader developing economic models and outcomes evidence for Natera’s precision cfDNA diagnostics. Supporting payer adoption, reimbursement, publications, and global market access.
Responsibilities:
- Lead development, validation, and application of health economic models, including budget impact, cost-effectiveness, cost-utility, cost-consequence, ROI, decision-tree, Markov/state-transition, and partitioned-survival models
- Develop scenario and sensitivity analyses quantifying the clinical and economic value of precision diagnostics
- Partner with Clinical Development, Medical Affairs, Biostatistics, and cross-functional teams to integrate HEOR objectives into prospective clinical studies
- Incorporate healthcare resource utilization, economic endpoints, patient-reported outcomes, quality-of-life measures, cost-data collection, and real-world evidence strategies into evidence plans
- Analyze clinical-trial, observational, and real-world datasets
- Evaluate resource utilization, cost of care, treatment pathways, diagnostic utilization, clinical utility, comparative effectiveness, patient outcomes, survival, budget impact, and quality-adjusted life years
- Lead HEOR publication strategy and develop manuscripts, abstracts, posters, oral presentations, white papers, and technical reports
- Coordinate publication plans with investigators, key opinion leaders, academic collaborators, and external research partners
- Translate HEOR evidence into payer value propositions, budget impact summaries, value dossiers, reimbursement materials, health economic briefs, value calculators, and account-specific economic tools
- Develop and adapt health economic evidence and payer models for U.S. and international markets
- Support reimbursement submissions and evidence strategies aligned with HTA and payer requirements
- Serve as a strategic HEOR partner across Medical Affairs, Clinical Development, Biostatistics, Market Access, Commercial, Marketing, Regulatory, and Business Development
- Collaborate with external consultants, academic investigators, KOLs, and research partners
Requirements:
- Advanced degree (PhD, PharmD, MD, DrPH, or Master's degree) in Health Economics, Outcomes Research, Epidemiology, Public Health, Biostatistics, Pharmacy, Health Services Research, or a related discipline
- 5–10+ years of HEOR experience within biotechnology, pharmaceuticals, diagnostics, medical devices, consulting, academia, or a related healthcare environment
- Demonstrated experience developing and applying health economic models and conducting outcomes research using clinical-trial and/or real-world datasets
- Experience supporting payer evidence generation, reimbursement strategy, value dossiers, market access initiatives, and scientific publications
- Experience with precision medicine, molecular diagnostics, companion diagnostics, ctDNA, molecular residual disease (MRD), donor-derived cell-free DNA (dd-cfDNA), next-generation sequencing, biomarker-guided treatment strategies, or oncology diagnostics is highly desirable
- Familiarity with Microsoft Excel, TreeAge Pro, R, SAS, STATA, Python, SQL, Tableau/Power BI, and statistical analysis software is preferred
Benefits:
- Annual performance incentive bonus
- Long-term equity awards
- Comprehensive health benefits (medical, dental, vision)
- 401(k) with company match
- Generous paid time off and company holidays
- Additional wellness and work-life benefits
- Life and disability plans for eligible employees and dependents
- Free testing for employees and immediate families
- Fertility care benefits
- Pregnancy and baby bonding leave
- Commuter benefits
- Employee referral program
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