Clinical Development Director – Cardiovascular
Employment Information
Report this job
Job expired or something wrong with this job?
Job Description
Lead medical and clinical development activities for cardiovascular assets at Amgen. Collaborate with cross-functional teams to drive clinical strategy and execution.
Responsibilities:
- Lead medical and clinical development activities for assets within the General Medicine therapeutic area
- Accountable for clinical strategy, study-level medical leadership, cross-functional decision-making, and support of program execution from early clinical development through late-stage studies
- Partner closely with Clinical Operations, Regulatory, Safety, Biostatistics, Medical Affairs, Data Management, and other functional teams
- Provide clinical and medical leadership for one or more General Medicine programs or studies
- Support the development, execution, and communication of global clinical development strategies for cardiovascular assets across all stages of development
- Collaborate with global teams to integrate medical, scientific, regulatory, commercial, and market access perspectives into development programs
- Build and maintain strategic scientific relationships with key opinion leaders and external experts
- Provide clinical and scientific leadership in the design, conduct, analysis, and interpretation of clinical trials
- Contribute to the authoring and review of clinical documents, safety evaluations, and risk-benefit assessments
- Participate in regulatory interactions and support submissions to global health authorities
- Interpret clinical trial results and contribute to data-driven development decisions
- Present scientific and clinical data at various forums as delegated by the Global Development Leader
- Identify emerging scientific opportunities and unmet medical needs in cardiovascular medicine to inform future development strategies
- Contribute to lifecycle management strategies and provide clinical content for regulatory submissions.
Requirements:
- MD or DO degree from an accredited medical school AND 2 years of clinical development experience
- 5+ years of clinical research experience and/or basic science research combined with clinical teaching and patient care activities in cardiovascular disease
- Clinical research experience in the biopharmaceutical industry (biotechnology, pharmaceutical, or CRO environment)
- Strong working knowledge of clinical trial design, execution, and interpretation, biostatistics, adaptive trial methodologies, and evidence-generation strategies
- Proven ability to work across matrixed teams and influence without direct authority
- Strong understanding of cardiovascular clinical endpoints, biomarkers, imaging modalities, and contemporary treatment guidelines
- Sound scientific and clinical judgment with the ability to evaluate complex benefit-risk profiles
- Working knowledge of Good Clinical Practice (GCP), FDA, EMA/CHMP regulations, ICH guidelines, and global regulatory requirements
- Excellent written and verbal communication skills, including the ability to communicate complex scientific concepts to diverse audiences
- Demonstrated success functioning as a medical leader within a highly matrixed global organization
- Strong strategic thinking, problem-solving, and decision-making capabilities with a track record of delivering results in complex development programs.
Benefits:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
- Group medical, dental and vision coverage
- Life and disability insurance
- Flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible.
Similar Jobs
Director, Network Management
Director of Network Management at Cigna Healthcare managing provider contracts and relationships. Leading strategic initiatives for provider contracting and partnerships in healthcare marketplace.
Senior Director – Pathology
Pathology Senior Director managing computational pathology workflows at Amgen. Leading the execution of AI/ML model development and ensuring quality data management in a research environment.
Director, Warehouse
Director of Warehouse overseeing Sysco's warehouse operations and driving strategy execution. Responsible for consistent execution of policies and procedures while leading staff and initiatives.
Associate Director, Medical Safety Review Physician
Medical Safety Review Physician conducting medical reviews of Individual Case Safety Reports at BeOne. Collaborating with teams to ensure compliance and safety signal detection.
Associate Director, Patient Services, Distribution Case Management
Case Manager supporting the myBeOne Patient Support Program and specialty pharmacy distribution network at BeOne. Providing exceptional customer service and collaboration with healthcare providers and internal stakeholders.
Associate Director, Patient Services and Distribution Case Management
Case Manager supporting myBeOne Patient Support Program and specialty pharmacy distribution network. Engaging with patients, healthcare providers, and internal stakeholders to facilitate therapy access.
Senior Director, Site Feasibility and Enablement, Americas
Senior Director leading site feasibility and engagement strategy across clinical development portfolio in the Americas for cancer trials. Focus on optimal site selection and patient recruitment strategies.
Area Director – Franchise Performance
Area Director responsible for driving performance across midscale and upper-midscale franchised hotels. Collaborates with stakeholders to enhance profitability, guest experience, and operational execution.
VIP BD Manager/Director – Global
BD Manager/Director driving institutional liquidity growth for crypto platform. Leveraging relationships and negotiating strategic partnerships for increased TVL.
Product Director
Product Director leading product strategy and development for compliance and risk solutions at SAI360. Coaching teams and driving outcomes for user-centered solutions in a collaborative environment.
Director, Media Strategy
Director of Media Strategy responsible for refining sports analytics products at Zoomph. Collaborating with cross-functional teams to drive product innovation and market engagement.
Director of Grants and Foundations
Director of Grants and Foundations leading institutional fundraising for All Hands & Hearts. Responsible for managing relationships and proposals across foundations and state funders.
Associate Director – Data Management
Director or Associate Director, Data Management at Codera overseeing clinical development programs. Responsible for data management leadership and vendor partnerships.
Senior Director, Information Systems – Health and Research
Information Systems Sr Director leading enterprise infrastructure supporting citizen services and research missions. Strategic leadership, team collaboration, and best practices in technology adoption and operational excellence.
Director of Client Engagement – Success
Director of Client Engagement overseeing family engagement strategy at AnswersNow, a virtual ABA therapy platform. Ensuring high retention and successful clinical outcomes for families with autism.
Director of Scaled Advising
Director of Scaled Advising leading national virtual advising programs at Bottom Line. Setting strategy and quality standards for advising, managing a high-performing team to support first-generation students.
Director, Program Strategy – Implementation
Director of Program Strategy & Implementation at Way to Win, a donor collaborative investing in long-term political power. Leading programs, initiatives, and relationships to strengthen democracy and advance change.
State Child Care Policy Director
State Child Care Policy Director at Child Care Aware of America driving child care policy research and advocacy. Leading strategic initiatives and managing coalitions for systemic improvements in child care.
Director
Director of Operations providing strategic leadership in logistics for DSV. Maximizing growth and profitability while ensuring operational excellence across core services.
Director, Implementation Services
Director of Implementation Services at Faro, leading implementation of AI-driven clinical trial design solutions. Responsible for customer integrations, technical delivery, and operational excellence.