Senior Director – Pathology
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Job Description
Pathology Senior Director managing computational pathology workflows at Amgen. Leading the execution of AI/ML model development and ensuring quality data management in a research environment.
Responsibilities:
- Ensure incoming datasets are delivered according to defined data formats, metadata standards, and project requirements.
- Translate scientific and model development requirements into structured dataset preparation tasks with pathology scientists and pathologists.
- Ensure imaging data, annotations, and metadata are suitable for downstream AI/ML model development, validation, and scientific analysis.
- Execute computational pathology workflows across AI model development and discovery projects for image analysis workflows to generate quantitative readouts supporting discovery and program decision-making within cloud-based data platforms (e.g., Deciphex Patholytics, Procia-Concentriq).
- Identify opportunities to improve data workflows, tooling, and operational processes within computational pathology.
- Stay informed about emerging data management practices, digital pathology technologies, and AI data standards.
- Provide pathology expertise to the design and conduct of GLP and non-GLP nonclinical safety studies to enable progression of discovery and development programs to decision points inclusive of pathology peer reviews and report review of integrated toxicology reports for finalization.
- Serve as a contributing author to pathology sections of regulatory documents such as INDs, NDA/BLAs, IBs, and respond to Health Authority questions.
Requirements:
- DVM and 7 years of pathology or toxicology experience OR Master’s degree and 10 years of pathology or toxicology experience OR Bachelor’s degree and 12 years of pathology or toxicology experience
- DVM, Board Certification in Veterinary Anatomic Pathology (DACVP or comparable credentialing body) and PhD in pathology or toxicology.
- At least 15 years’ experience in the pharmaceutical sector as a discovery and toxicologic pathologist and an additional 5 years’ experience integrating pathology data into bioinformatics efforts in a pharmaceutical environment.
- Experience in pathology data management within pharmaceutical environments is highly desirable.
- Demonstrated experience working with large-scale imaging datasets (e.g., whole-slide images) and associated metadata in distributed or cloud environments and analysis outputs.
- Experience with annotation platforms, digital pathology pipelines, or whole-slide image analysis environments.
- Familiarity with IHC assay workflows and digital slide scanning.
- Experience in interpreting dearly target discovery pathology and toxicology studies.
- Strong problem-solving skills and solution-oriented mindset, particularly when diagnosing and resolving data quality or workflow issues.
Benefits:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
- group medical, dental and vision coverage
- life and disability insurance
- flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible.
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