Director, Clinical Genomics Operations – Variant Science

Posted 2hrs ago

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Job Description

Director of Clinical Genomics Operations at Labcorp overseeing genomic interpretation and reporting. Leading operational strategies and mentoring teams in a clinical setting.

Responsibilities:

  • Provide strategic, technical, and operational leadership for clinical interpretation and reporting across WGS, WES, targeted NGS panels, and chromosomal microarray (CMA)
  • Serve as subject matter expert in genomic testing workflows, interpretation frameworks, and clinical reporting standards — ensuring scientific rigor, clinical relevance, and regulatory compliance
  • Oversee day-to-day operational performance including production scheduling, capacity planning, process health monitoring, and escalation of operational incidents
  • Establish, optimize, and scale end-to-end workflows for clinical interpretation and reporting using continuous improvement methodologies
  • Define, implement, and monitor key operational metrics to assess performance, identify risk, and communicate trends to senior leadership
  • Ensure delivery of high-quality clinical reports meeting established turnaround time, accuracy, and quality benchmarks
  • Lead root-cause analysis and implementation of corrective and preventive actions for complex production issues
  • Develop and execute operational strategies aligned with broader organizational OKRs
  • Mentor and coach scientists, genetic counselors, and operational partners — fostering a culture of continuous learning and scientific excellence
  • Collaborate cross-functionally with Laboratory, Bioinformatics, Product, Quality, Regulatory, IT, and Clinical Development to support launch of new assays, tools, and initiatives
  • Act as an individual-contributor Director with expectation of transitioning to formal people management within ~6 months

Requirements:

  • PhD in Biological Sciences, Molecular Genetics, or Human Genetics with 5 years or more of related work experience; OR Master's degree in Genetic Counseling, Biological Sciences, Molecular Genetics, or Human Genetics with 6 years or more of related work experience; OR Bachelor's degree in Genetics, Biological Sciences, Molecular Genetics, or Human Genetics with 7 years or more of related work experience
  • 3 years or more of demonstrated expertise in variant interpretation, curation, and clinical reporting for NGS-based assays, including WGS and WES and/or targeted panels
  • 3 years or more of experience driving operational efficiency and scaling production workflows supporting clinical interpretation and/or reporting
  • 3 years or more experience of demonstrated ability to coach, develop, and elevate operational or production teams, with strong organizational and execution skills
  • 3 years or more of experience managing or influencing complex initiatives with measurable outcomes in a high-throughput setting
  • 5 years or more of experience in operational leadership, including managing a team, workflow optimization, capacity planning, performance metrics, and cross-functional execution

Benefits:

  • Medical
  • Dental
  • Vision
  • Life
  • STD/LTD
  • 401(k)
  • Paid Time Off (PTO) or Flexible Time Off (FTO)
  • Tuition Reimbursement
  • Employee Stock Purchase Plan