Director, Clinical Genomics Operations – Variant Science
Posted 2hrs ago
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Job Description
Director of Clinical Genomics Operations at Labcorp overseeing genomic interpretation and reporting. Leading operational strategies and mentoring teams in a clinical setting.
Responsibilities:
- Provide strategic, technical, and operational leadership for clinical interpretation and reporting across WGS, WES, targeted NGS panels, and chromosomal microarray (CMA)
- Serve as subject matter expert in genomic testing workflows, interpretation frameworks, and clinical reporting standards — ensuring scientific rigor, clinical relevance, and regulatory compliance
- Oversee day-to-day operational performance including production scheduling, capacity planning, process health monitoring, and escalation of operational incidents
- Establish, optimize, and scale end-to-end workflows for clinical interpretation and reporting using continuous improvement methodologies
- Define, implement, and monitor key operational metrics to assess performance, identify risk, and communicate trends to senior leadership
- Ensure delivery of high-quality clinical reports meeting established turnaround time, accuracy, and quality benchmarks
- Lead root-cause analysis and implementation of corrective and preventive actions for complex production issues
- Develop and execute operational strategies aligned with broader organizational OKRs
- Mentor and coach scientists, genetic counselors, and operational partners — fostering a culture of continuous learning and scientific excellence
- Collaborate cross-functionally with Laboratory, Bioinformatics, Product, Quality, Regulatory, IT, and Clinical Development to support launch of new assays, tools, and initiatives
- Act as an individual-contributor Director with expectation of transitioning to formal people management within ~6 months
Requirements:
- PhD in Biological Sciences, Molecular Genetics, or Human Genetics with 5 years or more of related work experience; OR Master's degree in Genetic Counseling, Biological Sciences, Molecular Genetics, or Human Genetics with 6 years or more of related work experience; OR Bachelor's degree in Genetics, Biological Sciences, Molecular Genetics, or Human Genetics with 7 years or more of related work experience
- 3 years or more of demonstrated expertise in variant interpretation, curation, and clinical reporting for NGS-based assays, including WGS and WES and/or targeted panels
- 3 years or more of experience driving operational efficiency and scaling production workflows supporting clinical interpretation and/or reporting
- 3 years or more experience of demonstrated ability to coach, develop, and elevate operational or production teams, with strong organizational and execution skills
- 3 years or more of experience managing or influencing complex initiatives with measurable outcomes in a high-throughput setting
- 5 years or more of experience in operational leadership, including managing a team, workflow optimization, capacity planning, performance metrics, and cross-functional execution
Benefits:
- Medical
- Dental
- Vision
- Life
- STD/LTD
- 401(k)
- Paid Time Off (PTO) or Flexible Time Off (FTO)
- Tuition Reimbursement
- Employee Stock Purchase Plan


















